Tuesday, August 16, 2011

Supplementation during pregnancy


Vadillo-Ortega F, Perichart-Perera O et al. 2011. Effect of supplementation during pregnancy with L-arginine and antioxidant vitamins in medical food on pre-eclampsia in high risk population: randomised controlled trial. BMJ 342 (d2901).


Side effects were significantly more frequent in the group consuming L-arginine plus antioxidant vitamin bars than in the placebo group, including nausea (P=0.019), dyspepsia (P=0.04), dizziness (P=0.039), palpitations (P=0.019) and headache (P=0.01).Pre-eclampsia was defined as hypertension (systolic blood pressure [greater than or equal to]140 mm Hg, diastolic blood pressure [greater than or equal to]90 mm Hg or both) and proteinuria (>300 mg/24 hours) presenting after 20 weeks of gestation in women known to be previously normotensive.13,500mg of Amino Acids. Zero Sugar & Zero Aspartame. Great Taste!* With Free-Form BCAAs, Glutamine, Arginine & MorePre-eclampsia is a serious condition where abnormally high blood pressure and related pathology develop during pregnancy. It affects approximately 5% of first time pregnancies and is dangerous for both mother and child. Pre-eclampsia and eclampsia are among the leading causes of maternal and neonatal morbidity and mortality. A deficiency in L-arginine, the substrate for synthesis of the vasodilatory gas nitric oxide, may be associated with the development of pre-eclampsia in populations at high risk. Increased risk of pre-eclampsia is defined as either a personal history of pre-eclampsia or pre-eclampsia in a first degree relative.This study highlights the potential for L-arginine and antioxidant supplementation in reducing the risk of pre-eclampsia and associated preterm birth in women at risk of developing the condition.Leave it to the #1 selling bodybuilding supplement brand, MuscleTech[R], to formulate an ultra-premium amino-BCAA formula using only free-form amino acids and manufactured with the highes commitment to quality and science. With Team MuscleTech[R], you car trust that what's on the label is what's in the bottle.Participants were scheduled for clinical follow up every three to four weeks. All three intervention groups had a median of 5 (range 2-9) visits during the study. Follow up included arterial pressure measurement, 10 mL sample of venous blood (to determine L-arginine concentration), 24 hour urine sample (brought in by participant), evaluation of diary documenting consumption of bars (they were also required to bring in empty packets (confirming amount consumed) and nutritional education.High risk pregnant women between 14 and 32 weeks of gestation were recruited through a public hospital in Mexico City. Exclusion criteria included multiple gestation, known major fetal anomalies, diabetes (mellitus or gestational) pre existing hypertension, pre existing renal disease, collagen vascular disease, cancer or strong family history of cancer, and pre existing maternal disease needing drug treatment. Participants were randomly assigned to receive one of three treatments. Two hundred and twenty-two women were allocated to the placebo group, 228 received L-arginine (6.6 g) plus antioxidant vitamins (C, E and B vitamins), and 222 received antioxidant vitamins alone. The intervention was given in the form of food bars, each packaged and flavoured to look and taste the same.What's more? In a third-party scientific study conducted at the University of Sao Paulo with 20 subjects separated into two groups of 10, subjects using a specific ingredient combination available in just one daily scoop of NitroAminoFX for 8 weeks gained 9 times the muscle compared to control subjects (3.72 vs. 0.41 lbs.).* 13,500mg Amino Acid Matrix

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Author: Kathleen Murphy


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